Search on: PAIN INDIFFERENCE, CONGENITAL 
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Descriptor English:   Pain Insensitivity, Congenital 
Descriptor Spanish:   Insensibilidad Congénita al Dolor 
Descriptor Portuguese:   Insensibilidade Congênita à Dor 
Synonyms English:   Analgesia, Congenital
Pain Indifference, Congenital  
Tree Number:   C10.668.829.700
C16.320.775
Definition English:   A syndrome characterized by indifference to PAIN despite the ability to distinguish noxious from non-noxious stimuli. Absent corneal reflexes and INTELLECTUAL DISABILITY may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343) 
Indexing Annotation English:   congenital insensitivity to pain with anhidrosis = HSAN TYPE IV see NEUROPATHIES, HEREDITARY SENSORY AND AUTONOMIC; DF: PAIN INSENSITIVITY CONGEN
See Related English:   Hereditary Sensory and Autonomic Neuropathies
Pain
 
History Note English:   96; was ANALGESIA, CONGENITAL 1964-95 (Prov 1964-72); PAIN INSENSITIVITY, CONGENITAL was see ANALGESIA, CONGENITAL 1973-95 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications DI diagnosis
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RA radiography RI radionuclide imaging
RT radiotherapy RH rehabilitation
SU surgery TH therapy
US ultrasonography UR urine
VE veterinary VI virology
Record Number:   23943 
Unique Identifier:   D000699 

Occurrence in VHL:
 

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